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Article

Clonal hematopoiesis predicts development of therapy-related myeloid neoplasms post–autologous stem cell transplantation

9 Mar 2020

Abstract excerpt

Therapy-related myeloid neoplasms (tMN) develop after exposure to cytotoxic and radiation therapy, and due to their adverse prognosis, it is of paramount interest to identify patients at high risk. The presence of clonal hematopoiesis has been shown to increase the risk of developing tMN. The value of analyzing hematopoietic stem cells harvested at leukapheresis before autologous stem cell transplantation (ASCT)...

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PMID: 32150606
DOI: 10.1182/bloodadvances.2019001157

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