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Article

Modulation of Notch Signaling Pathway by Bioactive Dietary Agents

24 Mar 2022

Abstract excerpt

Notch signaling is often aberrantly activated in solid and hematological cancers and regulates cell fate decisions and the maintenance of cancer stem cells. In addition, increased expression of Notch pathway components is clinically associated with poorer prognosis in several types of cancer. Targeting Notch may have chemopreventive and anti-cancer effects, leading to reduced disease incidence and improved...

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PMID: 35408894
DOI: 10.3390/ijms23073532

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