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Article

Shared genetic correlations between kidney diseases and sepsis.

Frontiers in endocrinology - 1 Jan 2024

Zhang Tianlong, Cui Ying, Jiang Siyi, Jiang Lu, Song Lijun, Huang Lei, Li Yong, Yao Jiali, Li Min

Abstract excerpt

Background: Clinical studies have indicated a comorbidity between sepsis and kidney diseases. Individuals with specific mutations that predispose them to kidney conditions are also at an elevated risk for developing sepsis, and vice versa. This suggests a potential shared genetic etiology that has not been fully elucidated. Methods: Summary statistics data on exposure and outcomes were obtained from genome-wide...

Topics

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Genetic Pleiotropy
Genetic Predisposition to Disease
Genome-Wide Association Study
Kidney Diseases
Mendelian Randomization Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

Quantitative Trait Loci

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Identifiers

PMID: 39086896
DOI: 10.3389/fendo.2024.1396041
PMCID: PMC11288879

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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