Article
Genetic correlations and causal relationships between cardio-metabolic traits and sepsis.
Scientific reports - 8 Mar 2024
Zhang Zhongheng, Chen Lin, Zhang Haoyang, Xiao Wei, Yang Jie, Huang Jiajie, Hu Qichao, Jin Ketao, Hong Yucai
Abstract excerpt
Cardio-metabolic traits have been reported to be associated with the development of sepsis. It is, however, unclear whether these co-morbidities reflect causal associations, shared genetic heritability, or are confounded by environmental factors. We performed three analyses to explore the relationships between cardio-metabolic traits and sepsis. Mendelian randomization (MR) study to evaluate the causal effects of...
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