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Article

Primary sclerosing cholangitis causally affects kidney function decline: A Mendelian randomization study.

Journal of gastroenterology and hepatology - 1 Jan 2024

Cho Jeong Min, Koh Jung Hun, Kim Seong Geun, Lee Soojin, Kim Yaerim, Cho Semin, Kim Kwangsoo, Kim Yong Chul, Han Seung Seok, Lee Hajeong, Lee Jung Pyo, Joo Kwon Wook, Lim Chun Soo, Kim Yon Su, Kim Dong Ki, Park Sehoon

Abstract excerpt

BACKGROUND AND AIM: The causal linkage between primary sclerosing cholangitis (PSC) and kidney function is unexplored despite their potential for long-term detrimental effects on kidney function. METHODS: Two-sample summary-level Mendelian randomization (MR) study was conducted to identify the association between PSC and kidney function. The genetic variants were extracted from the PSC-specific multi-trait...

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Share to Cholangitis, Sclerosing
Share to Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Kidney

Share to Mendelian Randomization Analysis

Share to Polymorphism, Single Nucleotide

Share to Renal Insufficiency, Chronic

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PMID: 37726875
DOI: 10.1111/jgh.16355

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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