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Article

Structural basis for mouse receptor recognition by bat SARS2-like coronaviruses

31 Jul 2024

Abstract excerpt

The animal origin of SARS-CoV-2 remains elusive, lacking a plausible evolutionary narrative that may account for its emergence. Its spike protein resembles certain segments of BANAL-236 and RaTG13, two bat coronaviruses considered possible progenitors of SARS-CoV-2. Additionally, its spike contains a furin motif, a common feature of rodent coronaviruses. To explore the possible involvement of rodents in the...

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PMID: 39083418
DOI: 10.1073/pnas.2322600121

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