Article
Broad and Differential Animal Angiotensin-Converting Enzyme 2 Receptor Usage by SARS-CoV-2.
Journal of virology - 31 Aug 2020
Zhao Xuesen, Chen Danying, Szabla Robert, Zheng Mei, Li Guoli, Du Pengcheng, Zheng Shuangli, Li Xinglin, Song Chuan, Li Rui, Guo Ju-Tao, Junop Murray, Zeng Hui, Lin Hanxin
Abstract excerpt
The COVID-19 pandemic has caused an unprecedented global public health and economic crisis. The origin and emergence of its causal agent, SARS-CoV-2, in the human population remains mysterious, although bat and pangolin were proposed to be the natural reservoirs. Strikingly, unlike the SARS-CoV-2-like coronaviruses (CoVs) identified in bats and pangolins, SARS-CoV-2 harbors a polybasic furin cleavage site in its...
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