Examining the association between the FTO gene and neuroticism reveals indirect effects on subjective well-being and problematic alcohol use.

doi:10.1038/s41598-024-68578-2

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Examining the association between the FTO gene and neuroticism reveals indirect effects on subjective well-being and problematic alcohol use.

Scientific reports - 30 Jul 2024

Cai Wenjie, Forsell Yvonne, Lavebratt Catharina, Melas Philippe A

Abstract excerpt

Associations between the fat mass and obesity-associated (FTO) gene and obesity are well-established. However, recent studies have linked FTO to addiction phenotypes and dopaminergic signaling, thus suggesting broader psychiatric implications. We explored this assumption by conducting a phenome-wide association study across 4756 genome-wide association studies, identifying 23-26 psychiatric traits associated with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alcohol Drinking
Share to Alcoholism
Share to Alpha-Ketoglutarate-Dependent Dioxygenase FTO

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Body Mass Index

Share to Genetic Predisposition to Disease

Share to Genome-Wide Association Study

Share to Neuroticism

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 39080362
DOI: 10.1038/s41598-024-68578-2
PMCID: PMC11289395

Provenance

PubMed metadata and Literature Corpus relationships.