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Article

The role of the FTO gene in the relationship between depression and obesity. A systematic review.

Neuroscience and biobehavioral reviews - 1 Aug 2021

Zarza-Rebollo Juan Antonio, Molina Esther, Rivera Margarita

Abstract excerpt

Depression and obesity are major global health problems that frequently co-occur. The FTO gene has one of the strongest links with obesity and high body mass index (BMI) in humans. Besides, this gene is highly expressed in the brain, may play a role in the nervous system, and could confer risk for depression, although scarce literature is available in this respect. We perform a systematic review of the...

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Source

Identifiers

PMID: 34019853
DOI: 10.1016/j.neubiorev.2021.05.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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