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Article

FTO genotype and aging: pleiotropic longitudinal effects on adiposity, brain function, impulsivity and diet.

Molecular psychiatry - 1 Feb 2015

Chuang Y-F, Tanaka T, Beason-Held L L, An Y, Terracciano A, Sutin A R, Kraut M, Singleton A B, Resnick S M, Thambisetty M

Abstract excerpt

Although overweight and obesity are associated with poor health outcomes in the elderly, the biological bases of obesity-related behaviors during aging are poorly understood. Common variants in the FTO gene are associated with adiposity in children and younger adults as well as with adverse mental health in older individuals. However, it is unclear whether FTO influences longitudinal trajectories of adiposity and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24863145
DOI: 10.1038/mp.2014.49
PMCID: PMC4246032

Genes

FTO

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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