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Article

NLRP1B allele 2 does not respond to Val-boro-Pro (VbP) in intestinal epithelial cells.

Microbes and infection - 1 Jan 2024

Mazzone Ryan J, Winsor Nathaniel J, Li Lu Yi, Barry Kristian T, Ranger Adrienne, Goyal Shawn, Meade Justin J, Bruce Jessica, Philpott Dana J, Mogridge Jeremy, Girardin Stephen E

Abstract excerpt

The intestinal mucosa must balance tolerance to commensal microbes and luminal antigens with rapid detection of enteric pathogens in order to maintain homeostasis. This balance is facilitated through the regulation of epithelial layer integrity by innate immune receptors. Certain NOD-like receptors (NLRs) expressed in intestinal epithelial cells, including NLRC4 and NLRP9B, form inflammasomes that protect against...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 39047896
DOI: 10.1016/j.micinf.2024.105398

Genes

NLRC4
NLRP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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NLRP1B allele 2 does not respond to Val-boro-Pro (VbP) in intestinal epithelial cells.PMID 39047896Read ↗

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