Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Intestinal Epithelium-Specific MyD88 Signaling Impacts Host Susceptibility to Infectious Colitis by Promoting Protective Goblet Cell and Antimicrobial Responses

23 Jun 2014

Abstract excerpt

Intestinal epithelial cells (IECs), including secretory goblet cells, form essential physiochemical barriers that separate luminal bacteria from underlying immune cells in the intestinal mucosa. IECs are common targets for enteric bacterial pathogens, with hosts responding to these microbes through innate toll-like receptors that predominantly signal through the MyD88 adaptor protein. In fact, MyD88 signaling...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Clostridium difficile and Clostridium perfringens research
Share to Gut microbiota and health
Share to Inflammatory Bowel Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24958710
DOI: 10.1128/iai.02045-14

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Intestinal Epithelium-Specific MyD88 Signaling Impacts Host Susceptibility to Infectious Colitis by Promoting Protective Goblet Cell and Antimicrobial ResponsesPMID 24958710Read ↗

Epithelial-specific blockade of MyD88-dependent pathway causes spontaneous small intestinal inflammation.Semantic proximity Read ↗

Irgm1-deficiency leads to myeloid dysfunction in colon lamina propria and susceptibility to the intestinal pathogen <i>Citrobacter rodentium</i>Semantic proximity Read ↗

Intraepithelial lymphocytes exhibit selective immunity to intestinal pathogensSemantic proximity Read ↗

Establishing Boundaries: The Relationship That Exists between Intestinal Epithelial Cells and Gut-Dwelling BacteriaSemantic proximity Read ↗

Epithelial inflammasomes in the defense against Salmonella gut infectionSemantic proximity Read ↗

Giardia Infection of the Small Intestine Induces Chronic Colitis in Genetically Susceptible Hosts.Semantic proximity Read ↗

Epithelium-Intrinsic NAIP/NLRC4 Inflammasome Drives Infected Enterocyte Expulsion to Restrict Salmonella Replication in the Intestinal MucosaSemantic proximity Read ↗

Frontline defenders: goblet cell mediators dictate host-microbe interactions in the intestinal tract during health and diseaseSemantic proximity Read ↗

The Front Line of Enteric Host Defense against Unwelcome Intrusion of Harmful Microorganisms: Mucins, Antimicrobial Peptides, and MicrobiotaSemantic proximity Read ↗

Basic and Translational Understandings of Microbial Recognition by Toll-Like Receptors in the IntestineSemantic proximity Read ↗

Toll-interacting Protein Modulates Colitis Susceptibility in MiceSemantic proximity Read ↗

Mucins Dynamics in Physiological and Pathological ConditionsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.