Article

NLRP1B allele 2 does not respond to Val-boro-Pro (VbP) in the intestinal epithelium

2024-07-22

Abstract excerpt

<h4>ABSTRACT</h4> The intestinal mucosa must balance tolerance to commensal microbes and luminal antigens with rapid detection of enteric pathogens in order to maintain homeostasis. This balance is facilitated through the regulation of epithelial layer integrity by innate immune receptors. Certain NOD-like receptors (NLRs) expressed in intestinal epithelial cells, including NLRC4 and NLRP9B, form inflammasomes th...

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Literature Corpus work: 33927f06-655c-5384-b449-84a1a00fe036
DOI: 10.1101/2024.07.18.604161

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