Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Regulation of DMBT1 via NOD2 and TLR4 in intestinal epithelial cells modulates bacterial recognition and invasion.

Journal of immunology (Baltimore, Md. : 1950) - 15 Jun 2007

Rosenstiel Philip, Sina Christian, End Caroline, Renner Marcus, Lyer Stefan, Till Andreas, Hellmig Stephan, Nikolaus Susanna, Fölsch Ulrich R, Helmke Burkhard, Autschbach Frank, Schirmacher Peter, Kioschis Petra, Hafner Mathias, Poustka Annemarie, Mollenhauer Jan, Schreiber Stefan

Abstract excerpt

Mucosal epithelial cell layers are constantly exposed to a complex resident microflora. Deleted in malignant brain tumors 1 (DMBT1) belongs to the group of secreted scavenger receptor cysteine-rich proteins and is considered to be involved in host defense by pathogen binding. This report describe...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Calcium-Binding Proteins
Share to Crohn Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Intestinal Mucosa

Share to Lipopolysaccharides

Share to NF-kappa B

Share to Nod2 Signaling Adaptor Protein

Share to Salmonella enterica

Share to Toll-Like Receptor 4

Source

Identifiers

PMID: 17548659
DOI: 10.4049/jimmunol.178.12.8203

Genes

DMBT1
NOD2
TLR4
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17548659-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Regulation of DMBT1 via NOD2 and TLR4 in intestinal epithelial cells modulates bacterial recognition and invasion.PMID 17548659Read ↗

Intestinal DMBT1 expression is modulated by Crohn's disease-associated IL23R variants and by a DMBT1 variant which influences binding of the transcription factors CREB1 and ATF-2.Semantic proximity Read ↗

TLR Signaling in the Gut in Health and DiseaseSemantic proximity Read ↗

Nod2 in normal and abnormal intestinal immune function.Semantic proximity Read ↗

Nod2: a key regulator linking microbiota to intestinal mucosal immunity.Semantic proximity Read ↗

NOD2 Expression in Intestinal Epithelial Cells Protects Toward the Development of Inflammation and Associated CarcinogenesisSemantic proximity Read ↗

Nod2-Dependent Regulation of Innate and Adaptive Immunity in the Intestinal TractSemantic proximity Read ↗

Innate Immune Sensing of Microbes by Nod ProteinsSemantic proximity Read ↗

Recognition of peptidoglycan from the microbiota by Nod1 enhances systemic innate immunitySemantic proximity Read ↗

Bacterial interactions with cells of the intestinal mucosa: Toll-like receptors and NOD2.Semantic proximity Read ↗

The effect of NOD2 on the microbiota in Crohn's disease.Semantic proximity Read ↗

DMBT1 Confers Mucosal Protection In Vivo and a Deletion Variant Is Associated With Crohn’s DiseaseSemantic proximity Read ↗

The role of altered microbial signaling via mutant NODs in intestinal inflammation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.