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Article

Dysregulated NOD2 predisposes SAMP1/YitFc mice to chronic intestinal inflammation.

Proceedings of the National Academy of Sciences of the United States of America - 15 Oct 2013

Corridoni Daniele, Kodani Tomohiro, Rodriguez-Palacios Alexander, Pizarro Theresa T, Xin Wei, Nickerson Kourtney P, McDonald Christine, Ley Klaus F, Abbott Derek W, Cominelli Fabio

Abstract excerpt

Nucleotide-binding oligomerization domain-containing 2 (NOD2) is an intracellular receptor that plays an essential role in innate immunity as a sensor of a component of the bacterial cell wall, muramyl dipeptide (MDP). Crohn's disease (CD)-associated NOD2 variants lead to defective innate immune...

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Source

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Identifiers

PMID: 24082103
DOI: 10.1073/pnas.1311657110
PMCID: PMC3801018

Genes

NOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24082103-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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