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Article

E-Cadherin Mutational Landscape and Outcomes in Breast Invasive Lobular Carcinoma.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Oct 2024

Djerroudi Lounes, Bendali Amel, Fuhrmann Laetitia, Benoist Camille, Pierron Gaelle, Masliah-Planchon Julien, Kieffer Yann, Carton Matthieu, Tille Jean-Christophe, Cyrta Joanna, Ramtohul Toulsie, Bonneau Claire, Caly Martial, Renault Victor, Bidard François-Clément, Mechta-Grigoriou Fatima, Vincent-Salomon Anne

Abstract excerpt

Invasive lobular carcinomas (ILC) are characterized by the loss of E-cadherin expression and CDH1 gene inactivation. Diagnostic reproducibility for this tumor type is currently suboptimal and could be improved by a better understanding of its histomolecular and clinical heterogeneity. We have analyzed the relationship between the presence, type, or position of CDH1 mutations, E-cadherin expression, and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 39025406
DOI: 10.1016/j.modpat.2024.100570

Genes

CDH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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