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Article

Impact of different CEBPA mutations on therapeutic outcome in acute myeloid leukemia.

Annals of hematology - 1 Sept 2024

Zhao Yu, Huang Yun, Jiang Ling, Zhang Yujiao, Liu Fang, Yan Ping, Yu Guopan, Liu Jiajun, Jiang Xuejie

Abstract excerpt

Biallelic mutations of the CEBPA gene (CEBPAbi) are generally associated with favorable prognosis in patients with acute myeloid leukemia (AML). Monoallelic mutations of the CEBPA gene in carboxy-terminal DNA-binding region (CEBPAsmbZIP) and amino-terminal transactivation domains (CEBPAsmTAD) indicate distinct clinical characteristics and therapeutic outcomes. However, further investigation is required to fully...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39020042
DOI: 10.1007/s00277-024-05884-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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