Acute Myeloid Leukemia With CEBPA Mutations: Current Progress and Future Directions

Abstract excerpt

Mutations in CCAAT enhancer binding protein A gene ( CEBPA ) are one of the common genetic alterations in acute myeloid leukemia (AML). Recently, the emergence of new evidence makes it necessary to reconsider the subsets and treatment of AML patients with CEBPA mutations. This review will summarize the history of research progress of CEBPA mutations in AML, the heterogeneities of AML with CEBPA double mutations (...

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