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Article

Laboratory evaluation and prognostication among adults and children with CEBPA-mutant acute myeloid leukemia.

International journal of laboratory hematology - 1 Jul 2021

Mendoza Hadrian, Podoltsev Nikolai A, Siddon Alexa J

Abstract excerpt

CEBPA-mutant acute myeloid leukemia (AML) encompasses clinically and biologically distinct subtypes of AML in both adults and children. CEBPA-mutant AML may occur with monoallelic (moCEBPA) or biallelic (biCEBPA) mutations, which can be somatic or germline, with each entity impacting prognosis in unique ways. BiCEBPA AML is broadly associated with a favorable prognosis, but differences in the type and location of...

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PMID: 34288448
DOI: 10.1111/ijlh.13517

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