Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutations in the bZip region of the CEBPA gene: A novel prognostic factor in patients with acute myeloid leukemia.

International journal of laboratory hematology - 1 Dec 2023

Rivera Juan Carlos, Nuñez Daniel, Millar Elizabet, Ramirez Kimberly, Chandía Mauricio, Aguayo Claudio

Abstract excerpt

BACKGROUND: Hematopoiesis, the process of blood cell formation involves on a complex network of transcription factors. Among them, the CCAAT-enhancer-binding protein alpha (CEBPA) plays a crucial role in maintaining the balance between myeloid proliferation and differentiation. Imbalances in this network can lead to disrupted differentiation and contribute to the development of malignant diseases. AIM:...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CCAAT-Enhancer-Binding Proteins
Share to Leukemia, Myeloid, Acute

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Prognosis

Share to Transcription Factors

Source

Identifiers

PMID: 37621152
DOI: 10.1111/ijlh.14157

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutations in the bZip region of the CEBPA gene: A novel prognostic factor in patients with acute myeloid leukemia.PMID 37621152Read ↗

CEBPA mutations in acute myeloid leukemia: implications in risk stratification and treatment.Semantic proximity Read ↗

Characterization of CEBPA mutations in acute myeloid leukemia: most patients with CEBPA mutations have biallelic mutations and show a distinct immunophenotype of the leukemic cells.Semantic proximity Read ↗

Clinical Significance of bZIP In-Frame CEBPA-Mutated Normal Karyotype Acute Myeloid Leukemia.Semantic proximity Read ↗

CEBPA mutations in 4708 patients with acute myeloid leukemia: differential impact of bZIP and TAD mutations on outcome.Semantic proximity Read ↗

Acute Myeloid Leukemia With CEBPA Mutations: Current Progress and Future DirectionsSemantic proximity Read ↗

Complexity of CEBPA dysregulation in human acute myeloid leukemia.Semantic proximity Read ↗

Prognostic impact of CEBPA bZIP domain mutation in acute myeloid leukemia.Semantic proximity Read ↗

[Prognostic significance of CEBPA gene mutations in acute myeloid leukemia].Semantic proximity Read ↗

CEBPA bZIP in-frame mutations in acute myeloid leukemia: prognostic and therapeutic implicationsSemantic proximity Read ↗

Prevalence and prognostic implications of CEBPA mutations in pediatric acute myeloid leukemia (AML): a report from the Children's Oncology GroupSemantic proximity Read ↗

CEBPA gene mutations in Egyptian acute myeloid leukemia patients: impact on prognosis.Semantic proximity Read ↗

Acute Myeloid Leukemia With Biallelic CEBPA Gene Mutations and Normal Karyotype Represents a Distinct Genetic Entity Associated With a Favorable Clinical OutcomeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.