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Article

CEBPA mutations in acute myeloid leukemia: implications in risk stratification and treatment.

International journal of hematology - 1 Nov 2024

Tien Feng-Ming, Hou Hsin-An

Abstract excerpt

Mutations in CCAAT enhancer binding protein α (CEBPA) occur in approximately 10% of patients with de novo acute myeloid leukemia (AML). Emerging evidence supports that in-frame mutations in the basic leucine zipper domain of CEBPA (CEBPAbZIP-inf) confer a survival benefit, and CEBPAbZIP-inf replaced CEBPA double mutations (CEBPAdm) as a unique entity in the 2022 World Health Organization (WHO-2022) classification...

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Identifiers

PMID: 38671183
DOI: 10.1007/s12185-024-03773-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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