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Association of clonal hematopoiesis and mosaic chromosomal alterations with solid malignancy incidence and mortality

16 Jul 2024

Abstract excerpt

BACKGROUND: Understanding the impact of clonal hematopoiesis of indeterminate potential (CHIP) and mosaic chromosomal alterations (mCAs) on solid tumor risk and mortality can shed light on novel cancer pathways. METHODS: The authors analyzed whole genome sequencing data from the Trans-Omics for Precision Medicine Women's Health Initiative study (n = 10,866). They investigated the presence of CHIP and mCA and...

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PMID: 39012906
DOI: 10.1002/cncr.35455

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