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Article

Risk factors for clonal hematopoiesis of indeterminate potential and mosaic chromosomal alterations.

Translational research : the journal of laboratory and clinical medicine - 1 May 2023

Jakubek Yasminka A, Reiner Alexander P, Honigberg Michael C

Abstract excerpt

Clonal hematopoiesis of indeterminate potential (CHIP) and mosaic chromosomal alterations (mCAs) of the autosomes, X, and Y chromosomes are aging-related somatic mutations detectable in peripheral blood. The presence of these acquired mutations predisposes otherwise healthy adults to increased risk of several chronic aging-related conditions including hematologic cancers, atherosclerotic cardiovascular diseases,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36414227
DOI: 10.1016/j.trsl.2022.11.009
PMCID: PMC10135440

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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