Prevalence, Dynamics, and Prognostic Role of Clonal Hematopoiesis of Indeterminate Potential in Patients With Breast Cancer.

doi:10.1200/JCO.23.01071

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Prevalence, Dynamics, and Prognostic Role of Clonal Hematopoiesis of Indeterminate Potential in Patients With Breast Cancer.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 Nov 2024

Morganti Stefania, Gibson Christopher J, Jin Qingchun, Santos Katheryn, Patel Ashka, Wilson Alex, Merrill Margaret, Vincuilla Julie, Stokes Samantha, Lipsyc-Sharf Marla, Parker Tonia, King Tari A, Mittendorf Elizabeth A, Curigliano Giuseppe, Hughes Melissa E, Stover Daniel G, Tolaney Sara M, Weeks Lachelle D, Tayob Nabihah, Lin Nancy U, Garber Judy E, Miller Peter G, Parsons Heather A

Abstract excerpt

PURPOSE: Clonal hematopoiesis of indeterminate potential (CHIP) is frequent in patients with solid tumors. Prospective data about CHIP prevalence at breast cancer diagnosis and its dynamic evolution under treatment selective pressure are limited. PATIENTS AND METHODS: We performed targeted error-corrected sequencing on 614 samples from 380 patients with breast cancer. We investigated the dynamics of CHIP on...

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PMID: 38190580
DOI: 10.1200/JCO.23.01071
PMCID: PMC11795512

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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