Article
One-Week Kava Dietary Supplementation Increases Both Urinary N- and O-Glucuronides of NNAL, a Lung Carcinogen Major Metabolite, among Smokers.
Chemical research in toxicology - 16 Sept 2024
Hu Qi, Tang Zhixin, Lynch Allison, Freeman Breanne, Fujioka Naomi, Salloum Ramzi G, Malaty John, Orlando Frank A, Langaee Taimour, Huo Zhiguang, Xing Chengguo
Abstract excerpt
4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (commonly known as NNK) is one of the most prevalent and potent pulmonary carcinogens in tobacco products that increases the human lung cancer risk. Kava has the potential to reduce NNK and tobacco smoke-induced lung cancer risk by enhancing urinary excretion of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL, the major metabolite of NNK) and thus reducing...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.