Article

SWI/SNF nuclear foci scaffold peripheral gene hubs for circadian chromatin control

2026-02-06

Abstract excerpt

How dynamic circadian rhythms arise from a relatively static nuclear architecture remains a fundamental open question. Here, we identify the SWI/SNF chromatin-remodeling complex as a critical interface between the circadian clock and nuclear organization. Using endogenously tagged Moira (MOR), a core component of the Drosophila SWI/SNF complex and homolog of human BAF155, we find that MOR assembles into a small nu...

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Literature Corpus work: 21196603-6d6a-5c55-8cf0-85deba5784f4
DOI: 10.64898/2026.02.03.703661

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