Article
Clinicopathologic features and outcomes of acute leukemia harboring PICALM::MLLT10 fusion.
Human pathology - 1 Sept 2024
Wang Jeffrey, Zhang Weiwei, Xu Xinjie, Buglioni Alessia, Li Peng, Chen Xueyan, Liu Yajuan, Xu Min, Herrick Jennifer L, Horna Pedro, Zhang Xiaohui, Song Jinming, Jevremovic Dragan, He Rong, Shi Min, Yuan Ji
Abstract excerpt
The PICALM::MLLT10 fusion is a rare but recurrent cytogenetic abnormality in acute leukemia, with limited clinicopathologic and outcome data available. Herein, we analyzed 156 acute leukemia patients with PICALM::MLLT10 fusion, including 12 patients from our institutions and 144 patients from the literature. The PICALM::MLLT10 fusion preferentially manifested in pediatric and young adult patients, with a median...
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