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MLLT10 rearranged acute leukemia: Incidence, prognosis, and possible therapeutic strategies

28 Jul 2020

Abstract excerpt

Rearrangements of the MLLT10 gene occur in acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL), most commonly T-lineage ALL (T-ALL), in patients of all ages. MLLT10 rearranged (MLLT10r) acute leukemia presents a complex diagnostic and therapeutic challenge due to frequent presentation of immature or mixed phenotype, and a lack of consensus regarding optimal therapy. Cases of MLLT10r AML or T-ALL...

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PMID: 32720323
DOI: 10.1002/gcc.22887

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