Article
Differences in the mutational landscape of clonal hematopoiesis of indeterminate potential among races and between male and female patients with cancer.
Experimental hematology - 1 Oct 2024
Dhuri Kanaka, Alachkar Houda
Abstract excerpt
Clonal hematopoiesis of indeterminate potential (CHIP) has emerged as a significant precursor to hematological malignancies and is associated with several age-related diseases. We leveraged public data to explore differences in the mutational landscape of CHIP between males (Ms) and females (Fs) and across diverse racial populations. DNA (cytosine-5) methyltransferase 3 alpha (DNMT3A) mutations were substantially...
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