Article
Comparative analysis of genetic risk scores for predicting biochemical recurrence in prostate cancer patients after radical prostatectomy.
BMC urology - 2 Jul 2024
Hsieh Ai-Ru, Luo Yi-Ling, Bao Bo-Ying, Chou Tzu-Chieh
Abstract excerpt
BACKGROUND: In recent years, Genome-Wide Association Studies (GWAS) has identified risk variants related to complex diseases, but most genetic variants have less impact on phenotypes. To solve the above problems, methods that can use variants with low genetic effects, such as genetic risk score (GRS), have been developed to predict disease risk. METHODS: As the GRS model with the most incredible prediction power...
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