Article
Exome-based genome-wide association study and risk assessment using genetic risk score to prostate cancer in the Korean population.
Oncotarget - 4 Jul 2017
Oh Jong Jin, Lee Soo Ji, Hwang Joo-Yeon, Kim Dokyoon, Lee Sang Eun, Hong Sung Kyu, Ho Jin-Nyoung, Yoon Sungroh, Sung Joohon, Kim Wun-Jae, Byun Seok-Soo
Abstract excerpt
PURPOSE: To investigate exome-wide genetic variants associated with prostate cancer (PCa) in Koreans and evaluate the discriminative ability by the genetic risk score (GRS). PATIENTS AND METHODS: We prospectively recruited 1,001 PCa cases from a tertiary hospital and conducted a case-control study including 2,641 healthy men (Stage I). Participants were analyzed using HumanExome BeadChip. For the external...
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