Article
Genome-wide detection of allelic genetic variation to predict biochemical recurrence after radical prostatectomy among prostate cancer patients using an exome SNP chip.
Journal of cancer research and clinical oncology - 1 Aug 2015
Oh Jong Jin, Park Seunghyun, Lee Sang Eun, Hong Sung Kyu, Lee Sangchul, Lee Hak Min, Lee Jung Keun, Ho Jin-Nyoung, Yoon Sungroh, Byun Seok-Soo
Abstract excerpt
PURPOSES: Genetic variations among prostate cancer patients who underwent radical prostatectomies were evaluated to predict biochemical recurrence, and used to develop a clinical-genetic model that combines data on clinicopathological factors of prostate cancer and individual genetic variations. MATERIALS AND METHODS: We genotyped 242,186 SNPs on a custom HumanExome BeadChip v1.0 (Illuminam Inc.) from the blood...
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