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Article

Prediction of clinically significant prostate cancer using polygenic risk models in Asians.

Investigative and clinical urology - 1 Jan 2022

Song Sang Hun, Kim Eunae, Woo Eunjin, Kwon Eunkyung, Yoon Sungroh, Kim Jung Kwon, Lee Hakmin, Oh Jong Jin, Lee Sangchul, Hong Sung Kyu, Byun Seok-Soo

Abstract excerpt

PURPOSE: To develop and evaluate the performance of a polygenic risk score (PRS) constructed in a Korean male population to predict clinically significant prostate cancer (csPCa). MATERIALS AND METHODS: Total 2,702 PCa samples and 7,485 controls were used to discover csPCa susceptible single nucleotide polymorphisms (SNPs). Males with biopsy-proven or post-radical prostatectomy Gleason score 7 or higher were...

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Identifiers

PMID: 34983122
DOI: 10.4111/icu.20210305
PMCID: PMC8756152

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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