Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

γδ T cells in human colon adenocarcinomas comprise mainly Vδ1, Vδ2, and Vδ3 cells with distinct phenotype and function.

Cancer immunology, immunotherapy : CII - 2 Jul 2024

Rodin William, Szeponik Louis, Rangelova Tsvetanka, Tamiru Kebede Firaol, Österlund Tobias, Sundström Patrik, Hogg Stephen, Wettergren Yvonne, Cosma Antonio, Ståhlberg Anders, Bexe Lindskog Elinor, Quiding Järbrink Marianne

Abstract excerpt

Γδ T cell infiltration into tumours usually correlates with improved patient outcome, but both tumour-promoting and tumoricidal effects of γδ T cells have been documented. Human γδ T cells can be divided into functionally distinct subsets based on T cell receptor (TCR) Vδ usage. Still, the contribution of these different subsets to tumour immunity remains elusive. Here, we provide a detailed γδ T cell profiling...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma
Share to Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Colonic Neoplasms

Share to Lymphocytes, Tumor-Infiltrating

Share to Phenotype

Share to Receptors, Antigen, T-Cell, gamma-delta

Share to T-Lymphocyte Subsets

Source

Open in PubMed Open full text

Identifiers

PMID: 38953978
DOI: 10.1007/s00262-024-03758-7
PMCID: PMC11219682

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

γδ T cells in human colon adenocarcinomas comprise mainly Vδ1, Vδ2, and Vδ3 cells with distinct phenotype and function.PMID 38953978Read ↗

Progress of research on γδ T cells in colorectal cancer (Review)Semantic proximity Read ↗

Functional γδT-omics pipeline reveals compartmentalization of Vδ1⁺ T cell migration, tumor-reactivity, and clonality in human colorectal cancerSemantic proximity Read ↗

Dysfunctional tumor-infiltrating Vδ1 + T lymphocytes in microsatellite-stable colorectal cancerSemantic proximity Read ↗

Human γδ T cells in the tumor microenvironment: Key insights for advancing cancer immunotherapySemantic proximity Read ↗

Effector Vδ1 γδT cells mediate anti-tumor immunity and are reprogrammed by imatinib in human gastrointestinal stromal tumorSemantic proximity Read ↗

Gut γδ T cells as guardians, disruptors, and instigators of cancerSemantic proximity Read ↗

γδ T cells are effectors of immunotherapy in cancers with HLA class I defectsSemantic proximity Read ↗

A pan-cancer gamma delta T cell repertoireSemantic proximity Read ↗

Immune-Related Gene Expression and Cytokine Secretion Is Reduced Among African American Colon Cancer PatientsSemantic proximity Read ↗

Vγ9Vδ2 T Cell Response to Colon Carcinoma CellsSemantic proximity Read ↗

Deep characterization of human γδ T cell subsets defines shared and lineage-specific traits.Semantic proximity Read ↗

Localization-associated immune phenotypes of clonally expanded tumor-infiltrating T cells and distribution of their target antigens in rectal cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.