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LncRNA HULC augments high glucose‐associated pancreatic cancer progression and drug resistance by enhancing YAP activity and autophagy

1 Jul 2024

Abstract excerpt

BACKGROUND INFORMATION: One of the confounding factors in pancreatic cancer (PC) pathogenesis is hyperglycemia. The molecular mechanism by which high glucose (HG) influences PC severity is poorly understood. Our investigation delved into the impact of lncRNA highly upregulated in liver cancer (HULC) and its interaction with yes-associated protein (YAP) in regulating the fate of pancreatic ductal adenocarcinoma...

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Share to Autophagy in Disease and Therapy
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PMID: 38949568
DOI: 10.1111/boc.202400034

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