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Article

Opioid receptor polymorphism A118G associated with clinical severity in a drug overdose population.

Journal of medical toxicology : official journal of the American College of Medical Toxicology - 1 Jun 2013

Manini A F, Jacobs M M, Vlahov D, Hurd Y L

Abstract excerpt

Genetic variations in the human mu-opioid receptor gene (OPRM1) mediate individual differences in response to pain and opiate addiction. We studied whether the common A118G (rs1799971) mu-opioid receptor single nucleotide polymorphism (SNP) was associated with overdose severity in humans. In addi...

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Identifiers

PMID: 23318993
DOI: 10.1007/s13181-012-0286-3
PMCID: PMC3648633

Genes

OPRM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23318993-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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