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Article

Incidence of peritoneal cancer after oophorectomy among BRCA1 and BRCA2 mutation carriers.

Journal of the National Cancer Institute - 1 Nov 2024

Narod Steven A, Gronwald Jacek, Karlan Beth, Moller Pal, Huzarski Tomasz, Tung Nadine, Aeilts Amber, Eisen Andrea, Armel Susan Randall, Singer Christian F, Foulkes William D, Neuhausen Susan L, Olopade Olufunmilayo, Pal Tuya, Fruscio Robert, Metcalfe Kelly, Raj Rebecca, Jacobson Michelle, Sun Ping, Lubinski Jan, Kotsopoulos Joanne

Abstract excerpt

BACKGROUND: To estimate the incidence of primary peritoneal cancer after preventive bilateral oophorectomy in women with a BRCA1 or BRCA2 mutation. METHODS: A total of 6310 women with a BRCA1 or BRCA2 mutation who underwent a preventive bilateral oophorectomy were followed for a mean of 7.8 years from oophorectomy. The 20-year cumulative incidence of peritoneal cancer post-oophorectomy was estimated using the...

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Identifiers

PMID: 38937272
DOI: 10.1093/jnci/djae151
PMCID: PMC11542982

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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