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Article

Prophylactic salpingo-oophorectomy in BRCA1 mutation carriers and postoperative incidence of peritoneal and breast cancers.

Journal of ovarian research - 29 Feb 2016

Menkiszak Janusz, Chudecka-Głaz Anita, Gronwald Jacek, Cymbaluk-Płoska Aneta, Celewicz Aleksander, Świniarska Maria, Wężowska Małgorzata, Bedner Ryszard, Zielińska Dorota, Tarnowska Paulina, Jakubowicz Jerzy, Kojs Zbigniew

Abstract excerpt

BACKGROUND: There are no effective methods of diagnosis of early-stage ovarian cancer. Conservative care over patients at high risk of ovarian and breast cancers is ineffective. Prophylactic surgery is considered the best prophylaxis among BRCA1/BRCA2 carriers. METHODS: One hundred ninety-five patients, carriers of one of three most common mutations of the BRCA1 gene (Am J Hum Genet: 66: (6)1963-1968, 2000) in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26928677
DOI: 10.1186/s13048-016-0220-4
PMCID: PMC4772302

Genes

BRCA1
BRCA2

Provenance

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