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Peritoneal cancer risk after risk reducing salpingo-oophorectomy, impact of mutational status and STIC lesions.

Gynecologic oncology - 1 May 2026

Saule Claire, Laas Enora, Weber Nina, Bataillon Guillaume, Becette Veronique, Perlbarg-Samson Julie, Pouget Nicolas, Donnadieu Anne, Toussaint Aullène, Colas Chrystelle, Vincent-Salomon Anne, Frank Sophie, Pasmant Eric, Stoppa-Lyonnet Dominique, Fourchotte Virginie, Mouret-Fourme Emmanuelle

Abstract excerpt

BACKGROUND: Women with inherited susceptibility or a strong family history of ovarian cancer, particularly carriers of pathogenic BRCA1/2 variants, face a markedly increased lifetime risk. To mitigate this risk, current guidelines recommend risk-reducing salpingo-oophorectomy (RRSO) between ages 35 and 40 for BRCA1 and between ages 40 and 45 for BRCA2 METHODS: We conducted an ambispective multicenter study in...

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Identifiers

PMID: 41818853
DOI: 10.1016/j.ygyno.2026.02.019

Genes

BRCA1
PC
BRCA2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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