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DRAMATIC DIFFERENCE IN DIVERSITY BETWEEN PLASMODIUM FALCIPARUM AND PLASMODIUM VIVAX RETICULOCYTE BINDING-LIKE GENES

1 Jun 2005

Abstract excerpt

Malaria parasite proteins involved in erythrocyte invasion are considered important vaccine targets. Members of the reticulocyte binding-like (RBL) family of Plasmodium merozoite proteins are found in human, simian, and rodent malaria parasites and function in the initial steps of erythrocyte selection and invasion. The RBL genes are large, ranging in size from 7.7 to 10 kb, and the extent of any sequence...

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PMID: 15964948
DOI: 10.4269/ajtmh.2005.72.666

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