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Article

Respiratory Syncytial Virus Vaccine Design Using Structure-Based Machine-Learning Models.

Viruses - 22 May 2024

McCarty Thomas C, Vaisman Iosif I

Abstract excerpt

When designing live-attenuated respiratory syncytial virus (RSV) vaccine candidates, attenuating mutations can be developed through biologic selection or reverse-genetic manipulation and may include point mutations, codon and gene deletions, and genome rearrangements. Attenuation typically involves the reduction in virus replication, due to direct effects on viral structural and replicative machinery or viral...

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Identifiers

PMID: 38932114
DOI: 10.3390/v16060821
PMCID: PMC11209532

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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