Article
Associations between diabetes-related genetic risk scores and residual beta cell function in type 1 diabetes: the GUTDM1 study.
Diabetologia - 1 Sept 2024
Fuhri Snethlage Coco M, Balvers Manon, Ferwerda Bart, Rampanelli Elena, de Groen Pleun, Roep Bart O, Herrema Hilde, McDonald Timothy J, van Raalte Daniël H, Weedon Michael N, Oram Richard A, Nieuwdorp Max, Hanssen Nordin M J
Abstract excerpt
AIMS/HYPOTHESIS: Use of genetic risk scores (GRS) may help to distinguish between type 1 diabetes and type 2 diabetes, but less is known about whether GRS are associated with disease severity or progression after diagnosis. Therefore, we tested whether GRS are associated with residual beta cell function and glycaemic control in individuals with type 1 diabetes. METHODS: Immunochip arrays and TOPMed were used to...
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