Article
Type 1 Diabetes Genetic Risk Score: A Novel Tool to Discriminate Monogenic and Type 1 Diabetes.
Diabetes - 1 Jul 2016
Patel K A, Oram R A, Flanagan S E, De Franco E, Colclough K, Shepherd M, Ellard S, Weedon M N, Hattersley A T
Abstract excerpt
Distinguishing patients with monogenic diabetes from those with type 1 diabetes (T1D) is important for correct diagnosis, treatment, and selection of patients for gene discovery studies. We assessed whether a T1D genetic risk score (T1D-GRS) generated from T1D-associated common genetic variants provides a novel way to discriminate monogenic diabetes from T1D. The T1D-GRS was highly discriminative of proven...
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