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Article

Brain-Derived Neurotrophic Factor Val66Met is Associated with Variation in Cortical Structure in Healthy Aging Subjects.

Aging and disease - 1 Oct 2024

Shen Ting, Sheriff Samran, You Yuyi, Jiang Jiyang, Schulz Angela, Francis Heather, Mirzaei Mehdi, Saks Danit, Palanivel Viswanthram, Basavarajappa Devaraj, Chitranshi Nitin, Gupta Veer, Wen Wei, Sachdev Perminder S, Jia Huixun, Sun Xiaodong, Graham Stuart L, Gupta Vivek K

Abstract excerpt

Aging is associated with progressive brain atrophy and declines in learning and memory, often attributed to hippocampal or cortical deterioration. The role of brain-derived neurotrophic factor (BDNF) in modulating the structural and functional changes in the brain and visual system, particularly in relation to BDNF Val66Met polymorphism, remains underexplored. In this present cross-sectional observational study,...

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Identifiers

PMID: 38916728
DOI: 10.14336/AD.2024.0346
PMCID: PMC11346411

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BDNF

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