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Article

Improved pan-specific MHC class I peptide-binding predictions using a novel representation of the MHC-binding cleft environment.

Tissue antigens - 1 Feb 2014

Carrasco Pro S, Zimic M, Nielsen M

Abstract excerpt

Major histocompatibility complex (MHC) molecules play a key role in cell-mediated immune responses presenting bounded peptides for recognition by the immune system cells. Several in silico methods have been developed to predict the binding affinity of a given peptide to a specific MHC molecule. One of the current state-of-the-art methods for MHC class I is NetMHCpan, which has a core ingredient for the...

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Identifiers

PMID: 24447175
DOI: 10.1111/tan.12292
PMCID: PMC3925504

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