Article
Whole-genome sequencing of Mycobacterium tuberculosis for prediction of drug resistance.
Epidemiology and infection - 7 Jan 2022
Wang Luqi, Yang Jinghui, Chen Liang, Wang Weibing, Yu Fangyou, Xiong Haiyan
Abstract excerpt
Whole-genome sequencing (WGS) has shown tremendous potential in rapid diagnosis of drug-resistant tuberculosis (TB). In the current study, we performed WGS on drug-resistant Mycobacterium tuberculosis isolates obtained from Shanghai (n = 137) and Russia (n = 78). We aimed to characterise the underlying and high-frequency novel drug-resistance-conferring mutations, and also create valuable combinations of...
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