Article
Whole-genome sequencing-based analyses of drug-resistant Mycobacterium tuberculosis from Taiwan.
Scientific reports - 13 Feb 2023
Xiao Yu-Xin, Liu Kuang-Hung, Lin Wan-Hsuan, Chan Tai-Hua, Jou Ruwen
Abstract excerpt
Drug-resistant tuberculosis (DR-TB) posed challenges to global TB control. Whole-genome sequencing (WGS) is recommended for predicting drug resistance to guide DR-TB treatment and management. Nevertheless, data are lacking in Taiwan. Phenotypic drug susceptibility testing (DST) of 12 anti-TB drugs was performed for 200 Mycobacterium tuberculosis isolates. WGS was performed using the Illumina platform. Drug...
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