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Mycobacterium tuberculosis Next-Generation Whole Genome Sequencing: Opportunities and Challenges

9 Dec 2018

Abstract excerpt

Mycobacterium tuberculosis drug resistance is a threat to global tuberculosis (TB) control. Comprehensive and timely drug susceptibility determination is critical to inform appropriate treatment of drug-resistant tuberculosis (DR-TB). Phenotypic drug susceptibility testing (DST) is the gold standard for M. tuberculosis drug resistance determination. M. tuberculosis whole genome sequencing (WGS) has the potential...

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PMID: 30631597
DOI: 10.1155/2018/1298542

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