Thr92Ala-DIO2 heterozygosity is associated with skeletal muscle mass and myosteatosis in patients with COVID-19.

doi:10.1530/ETJ-24-0068

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Article

Thr92Ala-DIO2 heterozygosity is associated with skeletal muscle mass and myosteatosis in patients with COVID-19.

European thyroid journal - 1 Aug 2024

Beltrão Fabyan Esberard de Lima, Beltrão Daniele Carvalhal de Almeida, Carvalhal Giulia, Beltrão Fabyanna Lethicia de Lima, Oliveira Jocyel de Brito, Silva Hatilla Dos Santos, Teixeira Helena Mariana Pitangueira, Rodrigues Juliana Lopes, Figueiredo Camila Alexandrina Viana de, Costa Ryan Dos Santos, Hecht Fabio, Vieira Giciane Carvalho, Gonçalves Maria da Conceição Rodrigues, Bianco Antonio C, Ramos Helton Estrela

Abstract excerpt

Introduction: The type 2 deiodinase and its Thr92Ala-DIO2 polymorphism have been linked to clinical outcomes in acute lung injury and coronavirus disease 2019 (COVID-19). Objective: The objective was to identify a potential association between Thr92Ala-DIO2 polymorphism and body composition (appendicular muscle mass, myosteatosis, and fat distribution) and to determine whether they reflect the severity or...

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PMID: 38869458
DOI: 10.1530/ETJ-24-0068
PMCID: PMC11301567

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