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Article

Abdominal CT metrics in 17,646 patients reveal associations between myopenia, myosteatosis, and medical phenotypes: a phenome-wide association study.

EBioMedicine - 1 May 2024

Zambrano Chaves Juan M, Lenchik Leon, Gallegos Isabel O, Blankemeier Louis, Liang Tie, Rubin Daniel L, Willis Marc H, Chaudhari Akshay S, Boutin Robert D

Abstract excerpt

BACKGROUND: Deep learning facilitates large-scale automated imaging evaluation of body composition. However, associations of body composition biomarkers with medical phenotypes have been underexplored. Phenome-wide association study (PheWAS) techniques search for medical phenotypes associated with biomarkers. A PheWAS integrating large-scale analysis of imaging biomarkers and electronic health record (EHR) data...

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Identifiers

PMID: 38636199
DOI: 10.1016/j.ebiom.2024.105116
PMCID: PMC11031722

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